Efforts to find solutions aimed at restoring the balance between the sympathetic and parasympathetic divisions of the autonomic nervous system have been underway in Russia since the early 1970s. Solving this problem was necessary to facilitate astronauts' adaptation to long-term stays on space stations and to prevent the development of issues associated with increased sympathetic tone.

The use of medications in space is not always possible, as their effects in zero gravity are difficult to predict. Therefore, under the leadership of Professor Roman Baevsky, a world-renowned specialist in aviation and space cardiology and circulatory physiology under extreme conditions, the development of hardware methods for correcting sympathetic tone began.

This work took over a quarter of a century and ended in success. It was proven that influencing the balance of the autonomic nervous system through electrical impulses is possible. Another ten years were required to develop a universal, compact, and reliable device for use in any conditions. Medical engineer Alexander Gurov, one of the founders of the company "Inferum" and the creator of many unique electronic medical devices, made a tremendous contribution to this work.

The method of treating arterial hypertension using medium- and low-frequency electrical impulses, as well as the technology for creating a device for this purpose, were patented in 2014–2015. Vladislav Ivanov, Candidate of Technical Sciences and Chairman of the Board of Directors of the "Inferum" Group of Companies, organized the mass production of the ABP-051 at the company's own factory in Kamensk-Uralsky, certified under the international medical standard ISO 13485.